Scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, cause drowsiness, dilate the pupils, increase heart rate, and depress motor function. Management of drooling in disabled patients with scopolamine patches. It can be caused by pregnancy, false teeth, ulcers, acid reflux, and a broken jaw. Hypersalivation sialorrhoea is the excessive production of saliva. This is a more powerful antisecretory agent than hyoscine hydrobromide, and. The dose equivalent of a fentanyl 25 microgram patch is oral morphine 60 mg per.
Transdermal hyoscine patches scopolamine, scopoderm tts, novartis consumer. Each patch is a flat system of laminates, sealed around the edge, containing a clear oily filling. After oral or parenteral administration, its effects persist for 56 h, but this may be extended to up to 2472 h if the drug is administered transdermally via skin patches. In some cases, a healthcare provider will apply the patch just before your surgery. There is no effective conventional treatment of hyperlacrimation. Evidencebased information on hypersalivation can hyoscine hydrobromide be used to treat it from hundreds of trustworthy sources for health and social care. Hypersalivation can also be an adverse effect of drug treatment for example, clozapine. As scopolamine blocks parasympathetic innervation of the salivary glands, one of its indications is to reduce saliva secretion 14, 15.
The scopolamine transdermal skin patch is applied to a hairless area of skin just behind your ear. Sialorrhea or hyper salivation is an uncomfortable adverse effect that develops during treatment with antipsychotic medications. The combined transdermal patch and intraocular regimen may provide a safe. Scopoderm transdermal patches contain hyoscine hydrobromide. Ingestion of and exposure to transdermal patches should be. Hypersalivation can hyoscine hydrobromide be used to. Control of drooling using transdermal scopolamine skin patches. This presents as drooling in children, young people and adults with a neurological condition, such as cerebral palsy or parkinsons disease. It is a flat, round reservoir patch approximately 1. Topical administration is most likely to increase lacrimation compared with po. In addition, the use of imipramine tofranil 50150 mg. Hyoscine hydrobromide is taken to prevent travel sickness motion sickness.
Management of drooling in disabled patients with scopolamine. Drug therapy is a major cause of dry mouth and saliva production is affected. Guideline for managing guideline on management of drooling in. Guideline for the management of drooling in children. Lacrimation, sweating, headache, dizziness and cramps. It can also be used to reduce the amount of saliva in your mouth. Pdf evaluation of two scopolamine and physostigmine. Pharmacological management of hypersalivation in children and adults. Recognition and management of acute medication poisoning aafp.